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Clinical Trial Events
SCOPE Summit 2027

Panel Real World Evidence track

From RCT to Real World: Have We Really Bridged the Evidence Gap in the Era of Agentic AI?

Tue, Mar 2, 2027 · 12:20–12:45 PM EST Rosen Shingle Creek

About this session

Clinical trials and real-world evidence have long been viewed as complementary, yet they remain separated by differences in populations, treatment pathways, endpoints, data quality, and causal assumptions. This panel examines how far the field has progressed in truly connecting the two—from using RWD to inform trial design and external comparators to integrating trial and real-world evidence for effectiveness, safety, and regulatory decision-making—and asks the critical question: what is scientifically achievable today, and what remains unresolved?

Speakers

  • Xiaoyan Wang

    Professor, Health Policy and Management · Tulane University

    Moderator

  • Zhaoling Meng

    Associate Vice President & Global Head, Clinical Modeling & Evidence Integration · Sanofi

    Panelist

  • Sammi Rui Tang

    Senior Vice President & Global Head, Quantitative Sciences & Evidence Generation · Astellas Pharma, Inc.

    Panelist

  • Chunhua Weng

    Professor, Biomedical Informatics · Columbia University

    Panelist