Symposium 4: Neuroinflammation in Alzheimer's Disease: Targeting the NLRP3 Inflammasome and Neuroimmune Crosstalk

Tue, Nov 17, 2026 · 2:35–3:15 PM EST Ballroom - 4th floor, Boston Marriott Copley Place

About this session

Presentations: (1) Central-Peripheral Neuroimmune Crosstalk: Targeting Immune Dysfunction to Reduce Neurodegenerative Disease Progression; (2) NLRP3 regulates microglial immune and metabolic function in dementia; (3) The NLRP3 inflammasome as a therapeutic target in Alzheimer's disease: biomarker, preclinical evidence and Phase I healthy participants' safety data of the oral inhibitor RG6434.

Speakers

Malu Tansey

Indiana University School of Medicine

Chair
Róisín M. McManus

German Center for Neurodegenerative Diseases (DZNE)

Speaker
Gennaro Pagano

F. Hoffmann-La Roche Ltd

Speaker